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  Indian J Med Microbiol
 

Figure 4: Expression of CPT-1 and GLUT-4 mRNAs and protein in AngII-induced cardiac hypertrophy. (a) Expression of CPT-1 protein in the control, AngII, and SSYX (0.25, 0.5, and 1.0 μg/ml) groups. (b) Expression of GLUT-4 protein in each group. (c) Relative expression levels of CPT-1 mRNA in each group. (d) Relative expression levels of GLUT-4 mRNA in groups. (e) Expression of CPT-1 protein treated with 0.5 μg/ml SSYX for 0, 6, 12, 24, and 48 h. (f) Expression of GLUT-4 protein in each group. (g) Relative expression levels of CPT-1 mRNA in each group. (h) Relative expression levels of GLUT-4 mRNA in each group. *P < 0.0001 versus control group; P < 0.05 versus AngII group; *P < 0.05 versus 0 h; the data are expressed as the mean ± SD (n = 5, samples were collected from five different passages). The symbols “*, ” indicate that the value of CPT-1 and GLUT-4 mRNA expression significantly differed from different groups and durations. CPT-1: Carnitine acyltransferase enzyme-1; GLUT-4: Glucose transporter protein-4; mRNA: Messenger RNA; Ang: Angiotensin; SSYX: Shensong Yangxin Capsule; SD: Standard deviation.

Figure 4: Expression of CPT-1 and GLUT-4 mRNAs and protein in AngII-induced cardiac hypertrophy. (a) Expression of CPT-1 protein in the control, AngII, and SSYX (0.25, 0.5, and 1.0 μg/ml) groups. (b) Expression of GLUT-4 protein in each group. (c) Relative expression levels of <i>CPT-1</i> mRNA in each group. (d) Relative expression levels of <i>GLUT-4</i> mRNA in groups. (e) Expression of CPT-1 protein treated with 0.5 μg/ml SSYX for 0, 6, 12, 24, and 48 h. (f) Expression of GLUT-4 protein in each group. (g) Relative expression levels of <i>CPT-1</i> mRNA in each group. (h) Relative expression levels of <i>GLUT-4</i> mRNA in each group. *<i>P</i> < 0.0001 versus control group; <sup>†</sup><i>P</i> < 0.05 versus AngII group; *<i>P</i> < 0.05 versus 0 h; the data are expressed as the mean ± SD (<i>n</i> = 5, samples were collected from five different passages). The symbols “*, <sup>†</sup>” indicate that the value of <i>CPT-1</i> and <i>GLUT-4</i> mRNA expression significantly differed from different groups and durations. CPT-1: Carnitine acyltransferase enzyme-1; GLUT-4: Glucose transporter protein-4; mRNA: Messenger RNA; Ang: Angiotensin; SSYX: Shensong Yangxin Capsule; SD: Standard deviation.