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Year : 2018  |  Volume : 131  |  Issue : 16  |  Page : 1975-1982

Correlation of Betel Quid with Oral Cancer from 1998 to 2017: A Study Based on Bibliometric Analysis

1 Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China
2 Department of Health Policy, Institute of Medical Information, Chinese Academy of Medical Sciences, Beijing 100020, China
3 Department of Head and Neck Surgery, Hunan Cancer Hospital, Central South University, Changsha, Hunan 410008, China

Correspondence Address:
Dr. Hong Sun
Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0366-6999.238140

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Background: Betel quid chewing has been a major risk factor for oral cancer (OC) in southern China. This study aimed to analyze the scientific publications on the relationship between betel quid chewing and OC and construct a model to quantitatively and qualitatively evaluate pertinent publications from 1998 to 2017. Methods: The publications from 1998 to 2017 were retrieved from the Web of Science Core Collection database. Microsoft Excel, Thomson Data Analyzer, VOSviewer, and CiteSpace software were used to analyze the publication outcomes, journals, countries/regions, institutions, authors, research areas, and research frontiers. Results: A total of 788 publications on the relationship between betel quid chewing and OC published until October 25, 2017, were identified. The top 4 related journals were Journal of Oral Pathology Medicine, Oral Oncology, Plos One, and International Journal of Cancer. The top five countries engaged in related research included China, India, the United States, the United Kingdom, and Malaysia. The corresponding disciplines, such as oncology, oral surgery, pathology, environmental and occupational health, and toxicology, were mainly concentrated in three disciplines. The subject terms squamous cell carcinoma, OC, betel quid, expression, oral submucous fibrosis, India, and p53 ranked first among research hotspots. The burst terms squamous cell carcinoma, OC, betel quid, and expression ranked first in research frontiers. Conclusions: Research in this area emphasized hotspots such as squamous cell carcinoma, OC, oral submucosal fibrosis, betel quid, and tobacco. The annual number of publications steadily decreased from 1998 to 2017, with a lack of a systematic study from interdisciplinary perspectives, inadequate pertinent journals, limited regions with the practice of betel quid chewing, and insufficient participation of researchers, which indicate that as the prevalence of OC increases, particularly in China, research in this area warrants further expansion.


 Abstract in Chinese

1998 2017 年槟榔与口腔癌相关研究:基于研究文献的计量分析


背景:嚼食槟榔已成为中国南方地区口腔癌的主要危险因素。本研究旨在分析关于嚼食槟榔与口腔癌的关系的科学文献,建立自 1998 到 2017 年相关发表文献的数量和质量评估模型。

方法:从Web of Science 核心数据库检索自1998到2017年相关发表的文献。运用Microsoft Excel, Thomson Data Analyzer, VOSviewer 和 CiteSpace software 来分析文献来源、结果、杂志、国家/地区、机构、作者、研究领域和研究前沿热点。

结果:从 1998 到 2017 年10月25日,总共发表了 788 篇文献关于嚼食槟榔和口腔癌关系。排名前4的杂志分别为Journal of Oral Pathology Medicine,、Oral Oncology、Plos One 和 International Journal of Cancer. 参与研究的前5的国家包括中国、印度、美国、英国和马来西亚。相关的学科包括: oncology、 oral surgery、pathology、environment 、occupational health,、和toxicology. 其中研究主题词 squamous cell carcinoma、oral cancer, betel quid、expression、oral submucous fibrosis 和 p53 为主要研究热点。研究前沿热点的主题词包括 squamous cell carcinoma、oral cancer、betel quid 和 expression。

结论在该领域的研究研究热点包括squamous cell carcinoma、oral cancer、oral submucosal fibrosis、 betel quid和tobacco。但自1998 到 2017 年来,每年发表的相关文献逐年减少。从跨学科视角、缺乏较少的相关杂志、有限的研究领域和有限的相关研究人员等方面来看,该领域研究在系统性方面有所缺乏。以上结果表明,尤其在中国,随着口腔癌的发病率逐年升高,该领域的相关研究和探索需要进一步的拓展。

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